Biological capabilities

We possess a wide range of biological capabilities and we have access to extensive cutting-edge facilities.

Computer simulations

We can run computer simulations of diffusive dynamics, hydrodynamic interactions, anisotropic systems, rare events, biofilm growth, bacterial population growth in competitive and challenging environments.

Culturing bacteria and growth characterisation

For culturing bacteria and growth characterisation we have several plate readers (for OD, fluorescence, luminescence) and a liquid handling robot for high throughput growth curves. We can grow bacteria in complex media, do Fast Confocal microscopy, 3D microscopy and SPIM (Selective Plane Illumination Microscopy). We also have Cat 2 lab facilities.

DNA manipulation

We have expertise in optimization of DNA extraction methods, DNA sequencing, sequence analysis and other modern molecular biology techniques (e.g. qPCR, DGGE, WGA, etc).

Microbiology, molecular biology and nucleic acid biochemistry

To support experiments on microorganisms we can procure and grow microbiological strains while employing good microbiological practise. Molecular biology experience is used to construct and modify strains, for example, making deletion derivatives and modifying a strain to enable site specific labelling with fluorophores.  We are open to projects involving laboratory experiments with category 1 or 2 microorganisms.

Produce and genetically modify a range of bacteria

We can procure and grow microbiological strains while employing good microbiological practise. Molecular biology experience is used to construct and modify strains, for example, making deletion derivatives and modifying a strain to enable site specific labelling with fluorophores.

Study of bacteria in different conditions

We can study bacteria in different conditions. For example, at high pressure by using microscope pressure cells (image); in confinement by growing bacteria in microfluidic devices, inside droplets or in channels made with agarose gel. We can also study biofilm growth.